The National Institute on Drug Abuse (NIDA) is publishing a series of short videos on drug abuse that are really great. Check out this one titled "Addiction as a Brain Disease."
If you'd like to delve even deeper into the topic, you can check out Understanding Alcoholism as a Brain Disease: Book 2 of the ‘A Prescription for Alcoholics – Medications for Alcoholism’ Book Series (Rethinking Drinking) (Volume 2)
Although written from a medical perspective, this book is in plain language and super easy to understand.